Monday, March 17, 2014

Symptoms, Causes, & Risk Factors

As I discussed in my last post, Liver Cancer has a variety of different types, both primary and secondary.  Additionally, I spent some time defining what exactly cancer itself is before going too in depth about what liver cancer was.  Before you can do too much research about the other areas of liver cancer, it is extremely important that you understand what it is.  I highly suggest that if you need a refresher that you refer back to my last blog post in order to make sure you benefit from this next post as much as possible!  J

Now that we have a strong understanding of what exactly liver cancer is, we can start looking to answer another question about it.  What are the causes of liver cancer?  What are some of the symptoms of liver cancer?  If these are questions you are currently asking yourself about liver cancer, you should be able to answer these questions soon!

Liver that has suffered from Liver Cancer.
livercancersymptoms.org

What are some symptoms?

Unfortunately, most people don’t show signs of liver cancer when it’s in the early stages of development.  More times than not, symptoms of the common forms of primary liver cancer show before the more rare types.  As symptoms begin to appear patients may notice some of the following signs:
·        Weight loss, without trying
·        Loss of appetite
·        Upper abdominal pain
·        Nausea and vomiting
·        General weakness and fatigue
·        Abdominal swelling
·        Skin turning yellow, as well as whites of the eyes (jaundice)
·        White, chalky stools

Comparison of skin color for someone w/ and w/o jaundice.
www.puristat.com

As with any other type of sickness, or cancer, it is extremely important for patients to make an appointment with their doctor once these symptoms begin to appear.


What about causes?

At this point in time, researchers don’t have a clear answer for what exactly causes liver cancer.  However, they do have an idea of the cause in some cases.  One cause appears to be found when a patient has a hepatitis virus present within their body.  When this disease is present, infections tend to be long lasting, which in turn result in the development of liver cancer.  Just as I pointed out in my last post, liver cancer becomes present when the DNA within liver cells begins to form mutations.  Once this happens, the cells hold a strong possibility for growing out of control and developing a tumor.

Comparison between Liver Tissue.
13leesub.wordpress.com
Although researchers haven’t decided upon a clear cause for liver cancer, they have been able to uncover what appear to be some possible causes in patients who have been affected by liver cancer in the past.  Typically primary liver cancer develops when the liver has suffered some kind of damage.  This damage can happen through birth defects, alcohol abuse, and infections from diseases, such as Hepatitis as I discussed above.

Normal Liver vs. a Liver with Cirrhosis
depts.washington.edu

Risk Factors...?

Now that we have a better idea of the symptoms and causes of liver cancer, it’s important to also consider the risk factors that could put any one at risk for developing liver cancer.  A risk factor, according to the American Cancer Society, is anything that affects a person’s chance of getting a disease, such as cancer.  It is extremely important to keep in mind that just because a person meets some of these risk factors does not automatically mean they are at risk of developing liver cancer.  What these risk factors represent is what researchers have found to develop into liver cancer at some point in time with other patients.  Additionally, some patients who discover they have liver cancer sometimes do not meet any of the risk factors listed.  This shows just exactly how difficult and confusing liver cancer really is.

Some risk factors believed to lead to cancer include:
o   Gender: typically the most common form of liver cancer develops in men
o   Race: in the U.S. Asian Americans and Pacific Islanders have the highest rate of liver cancer development
o   Cirrhosis: disease where liver cells become damaged and are replaced by scar tissue
o   Chronic Viral Hepatitis, as I discussed above
o   Heavy alcohol use
o   Obesity
o   Type 2 Diabetes: patients with this risk factor typically fall under another risk factor as well
o   Inherited Metabolic Diseases: can lead to cirrhosis
o   Anabolic Steroids


Process of damaged liver due to alcohol consumption.
healthylivingguy.com
Although these are not the only risk factors for liver cancer, these tend to be some of the most popular risk factors among patients.

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