Thursday, May 1, 2014

Treatment of Liver Cancer

        So far we have looked through the multiple steps that lead up to one important factor when looking at liver cancer.  For many cancer patients, and their families, this step can sometimes be one of the toughest steps on the road to recovery.  This step that I am referring to is treatment.  When going through the battle of any type of cancer, this is one of the longest and toughest stages of the fighting process.  Before deciding what treatment option is right for you, the patient, it is important that you understand each of the options you have available.  It is important to keep in mind that the type of treatment you have available to you is also affected by the stage your cancer has been classified.

       Unfortunately, liver cancer is difficult to cure.  Primary liver cancer is difficult to detect in its early stages, as we discussed previously, when it can be treated most effectively.  Secondary liver cancer is difficult to treat because this means the cancer has already spread from another location within the body.  Because of the location of the liver within the body, surgery is quite difficult to complete due to the various blood vessels and bile ducts surrounding it.  With these ideas in mind, treatment for liver cancer tends to be strongly focused on simply making the patient feel better, more comfortable, and hopefully live longer than expected.

      Just like many other cancers, quite a few options are available to treatment, depending upon the stage one’s cancer is diagnosed.  Listed below are treatment options with brief descriptions that may be used for patients with liver cancer.  Also listed with treatment options are the side effects for each treatment type.  Each treatment type is likely to impact patients differently depending how their body is impacted by the treatment.  It is very important for patients to discuss treatment options over with their doctor because they will have the best idea about which treatment option will be the best for you, their patient.
·        

      Radiation Therapy

o  Radiation therapy consists of high-powered energy beams that target areas of the liver in order to shrink the tumor and/or destroy the cancer cells.
o   Side Effects:
§  Skin changes similar to that of sunburn: redness, peeling, blistering at the sight of radiation
§  Nausea and vomiting
§  Fatigue
§  Low blood counts
www.dvucancercare.com
            

       Chemotherapy

o   Chemotherapy is a drug that is used to treat cancer, aimed towards destroying the cancer cells.
o   Unfortunately, liver cancer usually rejects most chemo drugs.  They tend to only shrink the tumor very slightly, and these drugs don’t typically the response to the tumor and cancer cells doesn’t last very long.
o   Chemotherapy also comes with quite a few side effects:
§  Loss of hair
§  Mouth sores
§  Loss of appetite
§  Nausea and vomiting
§  Diarrhea
§  Low white blood cell accounts, leading to increased chance of infections
§  Low platelet counts, leading to easy bruising and bleeding
§  Fatigue, from low red blood cell count
www.ovca.org
        

       Surgery

o   Currently, surgery seems to offer patients the best chance for a true cure of liver cancer; however, this is only if all known cancer is removed.  Two common types of surgery for liver cancer patients includes resection, which is removal of the tumor, or a liver transplant.
o   Side effects from surgery (through removal)
§  Bleeding problems, from the inability to clot
§  Infections
§  Problems from anesthesia
§  Blood clots
§  Pneumonia
o   Side effects from liver transplant
§  Problems tend to arise from the drugs given to the patients to prevent their body from rejecting the liver transplant.
·         Increased risk of infection
·         High blood pressure
·         High cholesterol
·         Diabetes
·         Weakened bones and kidneys
·         Lead to new cancer
www.forerunnershealthcare.com
·         

       Tumor Ablation

o   This treatment focuses on destroying liver cancer cells without actually removing the cancer cells from the body.  Patients who use this form of treatment typically have only a few small tumors, and no more than 3 centimeters across, but aren’t a good candidate for surgery.  Although this form of treatment doesn’t work as well as surgery, it does work well for some patients and is typically used in patients waiting for a liver transplant.
o   Side effects:
§  Abdominal pain
§  Liver infections
§  Bleeding in the chest cavity or abdomen
www.cpmc.org
      

       Tumor Embolization

o   This form of treatment consists of injections of substances used to try and block/reduce the blood flow the cancer cells receive.  This option is used for students with cancerous tumors that cannot be removed through surgery.  Many times this form of treatment is used with ablation.
o   Side effects:
§  Abdominal pain
§  Fever
§  Nausea
§  Infection to the liver
§  Inflammation of the gallbladder
§  Blood clots within the vessels surrounding the liver

www.cigsurg.com

There are many times when a patient’s doctor is looking at treatment options that they will end up suggesting that their patient do a combination of two different treatments in order to get the most effective treatment possible for killing the cancer cells and shrinking the tumor.  No matter the circumstance, it is always important to discuss your options with your doctor to ensure you understand your best possible options.



Resources:
http://www.mayoclinic.org/diseases-conditions/liver-cancer/basics/treatment/con-20025222
http://www.webmd.com/cancer/understanding-liver-cancer-treatment
http://www.cancer.org/cancer/livercancer/detailedguide/liver-cancer-treating-general-info